Specific cleavage of transcription factors by the thiol protease, m-calpain.
The intracellular nonlysosomal calcium-dependent cysteine protease, m-calpain, is shown to specifically cleave the bHLHzip transcription factor USF leaving the binding and dimerisation domains intact. The resultant protein is capable of efficient DNA binding but is no longer able to activate transcr...
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| Udgivet i: | Nucleic Acids Res |
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| Principais autores: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
1993
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| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC310622/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8255762/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/21.22.5092 |
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