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Molecular cloning of a zinc finger protein which binds to the heptamer of the signal sequence for V(D)J recombination.

The somatic V(D)J recombination for the assembly of the Ig and TCR genes is mediated by the recombination signal sequences (Rss) and the V(D)J recombinase. A cDNA clone was isolated from a lambda gt11 expression library made from mouse thymocyte poly(A)+ RNA, using the Rss as a ligand. The deduced a...

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Autors principals: Wu, L C, Mak, C H, Dear, N, Boehm, T, Foroni, L, Rabbitts, T H
Format: Artigo
Idioma:Inglês
Publicat: 1993
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC310618/
https://ncbi.nlm.nih.gov/pubmed/8255760
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