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Biosynthesis of Promatrix Metalloproteinase-9/Chondroitin Sulphate Proteoglycan Heteromer Involves a Rottlerin-Sensitive Pathway

BACKGROUND: Previously we have shown that a fraction of the matrix metalloproteinase-9 (MMP-9) synthesized by the macrophage cell line THP-1 was bound to a chondroitin sulphate proteoglycan (CSPG) core protein as a reduction sensitive heteromer. Several biochemical properties of the enzyme were chan...

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Detalhes bibliográficos
Main Authors: Malla, Nabin, Berg, Eli, Moens, Ugo, Uhlin-Hansen, Lars, Winberg, Jan-Olof
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3105995/
https://ncbi.nlm.nih.gov/pubmed/21673806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0020616
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