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Neuronal Function and Dysfunction of Drosophila dTDP

BACKGROUND: TDP-43 is an RNA- and DNA-binding protein well conserved in animals including the mammals, Drosophila, and C. elegans. In mammals, the multi-function TDP-43 encoded by the TARDBP gene is a signature protein of the ubiquitin-positive inclusions (UBIs) in the diseased neuronal/glial cells...

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Detalhes bibliográficos
Main Authors: Lin, Meng-Jau, Cheng, Ching-Wei, Shen, C.-K. James
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3105987/
https://ncbi.nlm.nih.gov/pubmed/21673800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0020371
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