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Cloning and expression of the hypoxanthine-guanine phosphoribosyltransferase gene from Trypanosoma brucei.

The hypoxanthine-guanine phosphoribosyltransferase (HGPRT) enzyme of Trypanosoma brucei and related parasites provides a rational target for the treatment of African sleeping sickness and several other parasitic diseases. To characterize the T. brucei HGPRT enzyme in detail, the T. brucei hgprt was...

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Autors principals: Allen, T E, Ullman, B
Format: Artigo
Idioma:Inglês
Publicat: 1993
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC310582/
https://ncbi.nlm.nih.gov/pubmed/8265360
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