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Oligonucleotide circularization by template-directed chemical ligation.
An efficient method for producing the covalent closure of oligonucleotides on complementary templates by the action of BrCN was developed. A rational design of linear precursor oligonucleotides was studied, and the effect of factors such as oligonucleotide concentration and oligomer-template length...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
1993
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC310578/ https://ncbi.nlm.nih.gov/pubmed/8265356 |
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