Outcome of patients with chronic myeloid leukemia with multiple ABL1 kinase domain mutations receiving tyrosine kinase inhibitor therapy

We investigated the impact of carrying more than one BCR-ABL1 mutation in 207 patients with chronic myeloid leukemia (102 chronic, 61 accelerated, and 44 blast phase) post-imatinib failure. Seven (8%) of 92 patients carrying mutations had more than one mutation: 4 (4%) in chronic phase, 2 (2%) in ac...

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Detalhes bibliográficos
Main Authors: Quintás-Cardama, Alfonso, Kantarjian, Hagop, O’Brien, Susan, Jabbour, Elias, Borthakur, Gautam, Ravandi, Farhad, Verstovsek, Srdan, Shan, Jianqin, Cortes, Jorge
Formato: Artigo
Idioma:Inglês
Publicado em: Ferrata Storti Foundation 2011
Assuntos:
Brief Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3105655/
https://ncbi.nlm.nih.gov/pubmed/21357704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2010.039321
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