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Fc-DIRECTED ANTIBODY CONJUGATION OF MAGNETIC NANOPARTICLES FOR ENHANCED MOLECULAR TARGETING

In this study, we report the fabrication of engineered iron oxide magnetic nanoparticles (MNPs) functionalized with anti-human epidermal growth factor receptor type 2 (HER2) antibody to target the tumor antigen HER2. The Fc-directed conjugation of antibodies to the MNPs aids their efficient immunosp...

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Detalhes bibliográficos
Main Authors: REZAEIPOOR, ROBABEH, JOHN, RENU, ADIE, STEVEN G., CHANEY, ERIC J., MARJANOVIC, MARINA, OLDENBURG, AMY L., RINNE, STEPHANIE A., BOPPART, STEPHEN A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3105601/
https://ncbi.nlm.nih.gov/pubmed/21643439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1142/S1793545809000693
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