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Selective transmission of R5 HIV-1 variants: where is the gatekeeper?
To enter target cells HIV-1 uses CD4 and a coreceptor. In vivo the coreceptor function is provided either by CCR5 (for R5) or CXCR4 (for X4 HIV-1). Although both R5 and X4 HIV-1 variants are present in body fluids (semen, blood, cervicovaginal and rectal secretions), R5 HIV-1 appears to transmit inf...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
BioMed Central
2011
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3105506/ https://ncbi.nlm.nih.gov/pubmed/21284905 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-9-S1-S6 |
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