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A single trinucleotide, 5'AGC3'/5'GCT3', of the triplet-repeat disease genes confers metal ion-induced non-B DNA structure.

Expansion of (AGC)n repeats has been associated with genetic disorders called triplet-repeat diseases such as Huntington's disease (HD), myotonic muscular dystrophy (DM) and Kennedy's disease. To gain insight into the abnormal behavior of these repeats, we studied their structural properti...

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Bibliografske podrobnosti
Main Authors: Kohwi, Y, Wang, H, Kohwi-Shigematsu, T
Format: Artigo
Jezik:Inglês
Izdano: 1993
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC310530/
https://ncbi.nlm.nih.gov/pubmed/8284211
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