The monoamine oxidase (MAO) inhibitor tranylcypromine enhances nicotine self-administration in rats through a mechanism independent of MAO inhibition

Our current study aims to evaluate the mechanisms of tranylcypromine (TCP)-mediated enhancement of nicotine self-administration. We replicated our previous findings which demonstrate that 1-hr pretreatment with TCP (3mg/kg, i.p.) enhances nicotine self-administration (7.5 μg/kg/inj, i.v.) when compa...

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Bibliografiske detaljer
Main Authors: Lotfipour, Shahrdad, Arnold, Monica M., Hogenkamp, Derk J., Gee, Kelvin W., Belluzzi, James D., Leslie, Frances M.
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3105177/
https://ncbi.nlm.nih.gov/pubmed/21419142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2011.03.007
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