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Antibody-DM1 Conjugates as Cancer Therapeutics
Synthetic derivatives of the microtubule-targeted agent maytansine, commonly known as drug maytansinoids or DMs, are emerging as potential cancer therapeutics. DM1 is an antibody-conjugatable maytansinoid that was developed to overcome systemic toxicity associated with maytansine and to enhance tumo...
Αποθηκεύτηκε σε:
| Κύριος συγγραφέας: | |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2011
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3105156/ https://ncbi.nlm.nih.gov/pubmed/21481526 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2011.03.017 |
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