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Glutathione Restores the Mechanism of Synaptic Plasticity in Aged Mice to That of the Adult
Glutathione (GSH), the major endogenous antioxidant produced by cells, can modulate the activity of N-methyl-D-aspartate receptors (NMDARs) through its reducing functions. During aging, an increase in oxidative stress leads to decreased levels of GSH in the brain. Concurrently, aging is characterize...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3105108/ https://ncbi.nlm.nih.gov/pubmed/21655192 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0020676 |
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