Endogenous Synthesis of n-3 Polyunsaturated Fatty Acids in Fat-1 Mice Is Associated with Increased Mammary Gland and Liver Syndecan-1

Long chain n-3 PUFA have been shown to have chemopreventive properties against breast cancer through various mechanisms. One pathway, studied in human breast cancer cell lines, involves upregulation of the proteoglycan, syndecan-1 (SDC-1) by n-3 PUFA-enriched LDL. Using Fat-1 mice that are able to c...

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Detalhes bibliográficos
Main Authors: Sun, Haiguo, Hu, Yunping, Gu, Zhennan, Wilson, Martha D., Chen, Yong Q., Rudel, Lawrence L., Willingham, Mark C., Edwards, Iris J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3105073/
https://ncbi.nlm.nih.gov/pubmed/21655218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0020502
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