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Pooled Genotyping of Microsatellite Markers in Parent–Offspring Trios

We studied the extent to which genotyping of simple sequence repeat polymorphisms (SSRs) in pooled DNA samples can be used to predict differences in allele frequencies between parents and their affected offspring. We also developed a simple method of correction for the effects of stutter and differe...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Kirov, George, Williams, Nigel, Sham, Pak, Craddock, Nick, Owen, Michael J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2000
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC310506/
https://ncbi.nlm.nih.gov/pubmed/10645955
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