Colon-specific delivery of a probiotic-derived soluble protein ameliorates intestinal inflammation in mice through an EGFR-dependent mechanism

Probiotic bacteria can potentially have beneficial effects on the clinical course of several intestinal disorders, but our understanding of probiotic action is limited. We have identified a probiotic bacteria–derived soluble protein, p40, from Lactobacillus rhamnosus GG (LGG), which prevents cytokin...

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Autores principales: Yan, Fang, Cao, Hanwei, Cover, Timothy L., Washington, M. Kay, Shi, Yan, Liu, LinShu, Chaturvedi, Rupesh, Peek, Richard M., Wilson, Keith T., Polk, D. Brent
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 2011
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3104743/
https://ncbi.nlm.nih.gov/pubmed/21606592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI44031
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