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Stimulation of gene expression by introns: conversion of an inhibitory intron to a stimulatory intron by alteration of the splice donor sequence.

Efficient expression of many mammalian genes depends on the presence of at least one intron. We previously showed that addition of almost any of the introns from the mouse thymidylate synthase (TS) gene to an intronless TS minigene led to a large increase in expression. However, addition of intron 4...

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書誌詳細
出版年:Nucleic Acids Res
主要な著者: Korb, M, Ke, Y, Johnson, L F
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 1993
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC310472/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8290351/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/21.25.5901
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