STAT3 Knockdown in B16 Melanoma by siRNA Lipopolyplexes Induces Bystander Immune Response In Vitro and In Vivo

Persistent activation of STAT3 plays a major role in cancer progression and immune escape. Therefore, targeting STAT3 in tumors is essential to enhance/reactivate antitumor immune response. In our previous studies, we demonstrated the efficacy of stearic acid-modified polyethylenimine (PEI-StA) in p...

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Autors principals: Alshamsan, Aws, Hamdy, Samar, Haddadi, Azita, Samuel, John, El-Kadi, Ayman O S, Uludağ, Hasan, Lavasanifar, Afsaneh
Format: Artigo
Idioma:Inglês
Publicat: Neoplasia Press Inc. 2011
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3104698/
https://ncbi.nlm.nih.gov/pubmed/21633673
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