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Surface Export of GAPDH/SDH, a Glycolytic Enzyme, Is Essential for Streptococcus pyogenes Virulence

Streptococcal surface dehydrogenase (SDH) (glyceraldehyde-3-phosphate dehydrogenase [GAPDH]) is an anchorless major multifunctional surface protein in group A Streptococcus (GAS) with the ability to bind important mammalian proteins, including plasmin(ogen). Although several biological properties of...

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Detalhes bibliográficos
Main Authors: Jin, Hong, Agarwal, Shivangi, Agarwal, Shivani, Pancholi, Vijay
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Microbiology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3104492/
https://ncbi.nlm.nih.gov/pubmed/21628503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00068-11
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