Epstein-Barr Virus Nuclear Protein 3C binds to the N-terminal (NTD) and beta trefoil domains (BTD) of RBP/CSL; only the NTD interaction is essential for lymphoblastoid cell growth

Association of EBV nuclear proteins EBNA2, EBNA3A and EBNA3C with RBP/CSL, is essential for lymphoblastoid cell line (LCL) proliferation. Conserved residues in the EBNA3 homology domain, required for RBP/CSL interaction, lack the WΦP motif that mediates EBNA2 and Notch binding to the RBP/CSL beta-tr...

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Detalhes bibliográficos
Main Authors: Calderwood, Michael A, Lee, Sungwook, Holthaus, Amy M, Blacklow, Stephen C, Kieff, Elliott, Johannsen, Eric
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3104408/
https://ncbi.nlm.nih.gov/pubmed/21440926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2011.02.018
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