Infection of human monocyte-derived dendritic cells by ANDES Hantavirus enhances pro-inflammatory state, the secretion of active MMP-9 and indirectly enhances endothelial permeability

BACKGROUND: Andes virus (ANDV), a rodent-borne Hantavirus, is the major etiological agent of Hantavirus cardiopulmonary syndrome (HCPS) in South America, which is mainly characterized by a vascular leakage with high rate of fatal outcomes for infected patients. Currently, neither specific therapy no...

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Autores principales: Marsac, Delphine, García, Stephanie, Fournet, Alexandra, Aguirre, Adam, Pino, Karla, Ferres, Marcela, Kalergis, Alexis M, Lopez-Lastra, Marcelo, Veas, Francisco
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3104372/
https://ncbi.nlm.nih.gov/pubmed/21569520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-8-223
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