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A probabilistic approach to identify putative drug targets in biochemical networks

Network-based drug design holds great promise in clinical research as a way to overcome the limitations of traditional approaches in the development of drugs with high efficacy and low toxicity. This novel strategy aims to study how a biochemical network as a whole, rather than its individual compon...

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Autors principals: Murabito, Ettore, Smallbone, Kieran, Swinton, Jonathan, Westerhoff, Hans V., Steuer, Ralf
Format: Artigo
Idioma:Inglês
Publicat: The Royal Society 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3104352/
https://ncbi.nlm.nih.gov/pubmed/21123256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsif.2010.0540
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