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Human hydroxysteroid dehydrogenases and pre-receptor regulation: Insights into inhibitor design and evaluation
Hydroxysteroid dehydrogenases (HSDs) represent a major class of NAD(P)(H) dependent steroid hormone oxidoreductases involved in the pre-receptor regulation of hormone action. This is achieved by HSDs working in pairs so that they can interconvert ketosteroids with hydroxysteroids resulting in a chan...
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2011
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| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3104102/ https://ncbi.nlm.nih.gov/pubmed/21272640 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsbmb.2011.01.009 |
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