Comparing cellular uptake and cytotoxicity of targeted drug carriers in cancer cell lines with different drug resistance mechanisms

The purpose of this study was to compare the cellular uptake and cytotoxicity of targeted and nontargeted doxorubicin (DOX)-loaded poly(d,l-lactide co-glycolide) (PLGA) nanoparticle (NP) drug delivery systems in drug-resistant ovarian (SKOV-3) and uterine (MES-SA/Dx5) cancer cell lines. The cellular...

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Detalhes bibliográficos
Main Authors: Lei, Tingjun, Srinivasan, Supriya, Tang, Yuan, Manchanda, Romila, Nagesetti, Abhignyan, Fernandez-Fernandez, Alicia, McGoron, Anthony J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3104086/
https://ncbi.nlm.nih.gov/pubmed/21094277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nano.2010.11.004
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