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A One and a Two…Expanding Roles for Poly(ADP-ribose) Polymerases in Metabolism
In two related papers in this issue, Bai et al. (2011a; 2011b) observe that PARP-1- or PARP-2-deficient mice show increased energy expenditure and protection against diet-induced obesity. This metabolic phenotype is achieved, in part, through SIRT1 activation, either by increasing NAD(+) levels or b...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3104020/ https://ncbi.nlm.nih.gov/pubmed/21459317 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2011.03.011 |
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