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The role of a minor groove spine of hydration in stabilizing poly(dA).poly(dT) against fluctuational interbase H-bond disruption in the premelting temperature regime.

Experimental estimates of the premelting Adenine-Thymine base pair opening probability for some B-DNA sequences are two orders of magnitude smaller than those of other B-DNA sequences. The AT pairs in the sequence with smaller open probability seem to be those that have a well defined spine of hydra...

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Publicat a:Nucleic Acids Res
Autors principals: Chen, Y Z, Prohofsky, E W
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 1992
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC310401/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1741275/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/20.3.415
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