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Cyclophosphamide resets dendritic cell homeostasis and enhances antitumor immunity through effects that extend beyond regulatory T cell elimination

Using a model of established malignancy, we found that cyclophosphamide (Cy), administered at a dose not requiring hematopoietic stem cell support, is superior to low-dose total body irradiation in augmenting antitumor immunity. We observed that Cy administration resulted in expansion of tumor antig...

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Detalhes bibliográficos
Main Authors: Radojcic, Vedran, Bezak, Karl B., Skarica, Mario, Pletneva, Maria A., Yoshimura, Kiyoshi, Schulick, Richard D., Luznik, Leo
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3103867/
https://ncbi.nlm.nih.gov/pubmed/19590872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-009-0734-3
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