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Ski and SnoN, potent negative regulators of TGF-β signaling

Ski and the closely related SnoN were discovered as oncogenes by their ability to transform chicken embryo fibroblasts upon overexpression. While elevated expressions of Ski and SnoN have also been reported in many human cancer cells and tissues, consistent with their pro-oncogenic activity, emergin...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Deheuninck, Julien, Luo, Kunxin
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3103856/
https://ncbi.nlm.nih.gov/pubmed/19114989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2008.324
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