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Proteasome inhibitor treatment in alcoholic liver disease
Oxidative stress, generated by chronic ethanol consumption, is a major cause of hepatotoxicity and liver injury. Increased production of oxygen-derived free radicals due to ethanol metabolism by CYP2E1 is principally located in the cytoplasm and in the mitochondria, which does not only injure liver...
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Baishideng Publishing Group Co., Limited
2011
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3103814/ https://ncbi.nlm.nih.gov/pubmed/21633661 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v17.i20.2558 |
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