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Phase 1 Randomized Trial of the Vaginal Safety and Acceptability of SPL7013 Gel (VivaGel(®)) in Sexually Active Young Women (MTN-004)

OBJECTIVES: The study was designed to assess the safety, adherence, acceptability, and effect on vaginal microflora of 3% SPL7013 Gel (VivaGel(®)), a novel dendrimer topical microbicide that inhibits HIV, HSV-2 and HPV in vitro and in animal models. DESIGN: Phase 1, randomized, double-blind, placebo...

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Main Authors: MCGOWAN, Ian, GOMEZ, Kailazarid, BRUDER, Karen, FEBO, Irma, CHEN, Beatrice A, RICHARDSON, Barbra A, HUSNIK, Marla, LIVANT, Edward, PRICE, Clare, Jacobson, Cindy
Formato: Artigo
Idioma:Inglês
Publicado: 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3103767/
https://ncbi.nlm.nih.gov/pubmed/21505316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAD.0b013e328346bd3e
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