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Numb links extracellular cues to intracellular polarity machinery to promote chemotaxis
Cell polarization is essential throughout development for proliferation, migration and differentiation. However, it is not known how extracellular cues correctly orient cell polarity at distinct stages of development. Here we show that the endocytic adapter protein, Numb, previously characterized fo...
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| Main Authors: | , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2011
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3103748/ https://ncbi.nlm.nih.gov/pubmed/21571219 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2011.04.006 |
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