Substitutions of a cysteine conserved among DNA cytosine methylases result in a variety of phenotypes.
The proposed mechanism for DNA (cytosine-5)-methyltransferases envisions a key role for a cysteine residue. It is expected to form a covalent link with carbon 6 of the target cytosine, activating the normally inactive carbon 5 for methyl transfer. There is a single conserved cysteine among all DNA (...
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| Veröffentlicht in: | Nucleic Acids Res |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
1992
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| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC310373/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1371346/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/20.2.319 |
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