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Mutations in PA, NP, and HA of a pandemic (H1N1) 2009 influenza virus contribute to its adaptation to mice

In 2009, a swine-origin H1N1 influenza virus caused the first pandemic of the 21st century. To understand the molecular basis of pandemic influenza virus adaptation to new host species, we serially passaged the pandemic (H1N1) 2009 virus strain A/California/04/09 in mouse lungs. After ten passages,...

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Autors principals: Sakabe, Saori, Ozawa, Makoto, Takano, Ryo, Iwastuki-Horimoto, Kiyoko, Kawaoka, Yoshihiro
Format: Artigo
Idioma:Inglês
Publicat: 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3103651/
https://ncbi.nlm.nih.gov/pubmed/21458512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virusres.2011.03.022
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