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Drosophila lacking a homologue of mammalian ALDH2 have multiple fitness defects

Little is known about the roles of aldehyde dehydrogenases in non-vertebrate animals. We recently showed that in Drosophila melanogaster, an enzyme with ~70% amino acid identity to mammalian ALDH2 is necessary for detoxification of dietary ethanol. To investigate other functions of this enzyme, DmAL...

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Detalhes bibliográficos
Main Authors: Chakraborty, Mahul, Fry, James D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3103639/
https://ncbi.nlm.nih.gov/pubmed/21296060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbi.2011.01.031
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