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Glycogen synthase kinse-3 regulates endoplasmic reticulum (ER) stress-induced CHOP expression in neuronal cells

Endoplasmic reticulum (ER) stress, often resulting from cellular accumulation of misfolded proteins, occurs in many neurodegenerative disorders, in part because of the relatively long lifetime of neurons. Excessive accumulation of misfolded proteins activates the unfolded protein response (UPR) that...

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Detalhes bibliográficos
Main Authors: Meares, Gordon P., Mines, Marjelo A., Beurel, Eleonore, Eom, Tae-Yeon, Song, Ling, Zmijewska, Anna A., Jope, Richard S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3103628/
https://ncbi.nlm.nih.gov/pubmed/21356208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2011.02.012
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