Molecular and functional analysis of the XPBC/ERCC-3 promoter: transcription activity is dependent on the integrity of an Sp1-binding site.

The human XPBC/ERCC-3 gene, which corrects the excision-repair defect in xeroderma pigmentosum group B cells and the UV-sensitive CHO mutant 27-1 cells, appears to be expressed constitutively in various cell types and tissues. We have analysed the structure and functionality of the XPBC/ERCC-3 promo...

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Hlavní autoři: Ma, L, Weeda, G, Jochemsen, A G, Bootsma, D, Hoeijmakers, J H, van der Eb, A J
Médium: Artigo
Jazyk:Inglês
Vydáno: 1992
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC310357/
https://ncbi.nlm.nih.gov/pubmed/1741247
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