Secretoglobin 3A2 Suppresses Bleomycin-induced Pulmonary Fibrosis by Transforming Growth Factor β Signaling Down-regulation

With increasing worldwide rates of morbidity and mortality of pulmonary fibrosis, the development of effective therapeutics for this disease is of great interest. Secretoglobin (SCGB) 3A2, a novel cytokine-like molecule predominantly expressed in pulmonary airways epithelium, exhibits anti-inflammat...

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Autori principali: Kurotani, Reiko, Okumura, Satoshi, Matsubara, Tsutomu, Yokoyama, Utako, Buckley, John R., Tomita, Takeshi, Kezuka, Kyohei, Nagano, Tomokazu, Esposito, Dominic, Taylor, Troy E., Gillette, William K., Ishikawa, Yoshihiro, Abe, Hiroyuki, Ward, Jerrold M., Kimura, Shioko
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2011
Soggetti:
Molecular Bases of Disease
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3103347/
https://ncbi.nlm.nih.gov/pubmed/21478551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.239046
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