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Divergent mechanisms for trophic actions of estrogens in the brain and peripheral tissues

17β-estradiol (E(2)) can enhance reproductive, cognitive, and affective functions; however, the mechanisms by which E(2) has these effects need to be better understood. Pleiotrophic effects of E(2) can occur via traditional and novel actions at various forms of estrogen receptors (ERs). In the centr...

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Autors principals: Walf, Alicia A., Paris, Jason J., Rhodes, Madeline E., Simpkins, James W., Frye, Cheryl A.
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3103067/
https://ncbi.nlm.nih.gov/pubmed/21130078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2010.11.081
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