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Reelin, Rap1 and N-cadherin orient the migration of multipolar neurons in the developing neocortex

Projection neurons migrate from the ventricular zone to the neocortical plate during mouse brain development. Their overall movement is radial, but they become multipolar and move non-radially in the intermediate zone. Here we show that Reelin, the Rap1 GTPase, and N-cadherin (NCad) are important fo...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Jossin, Yves, Cooper, Jonathan A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3102785/
https://ncbi.nlm.nih.gov/pubmed/21516100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.2816
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