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Integrated Genome-Scale Prediction of Detrimental Mutations in Transcription Networks
A central challenge in genetics is to understand when and why mutations alter the phenotype of an organism. The consequences of gene inhibition have been systematically studied and can be predicted reasonably well across a genome. However, many sequence variants important for disease and evolution m...
में बचाया:
मुख्य लेखकों: | , , |
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स्वरूप: | Artigo |
भाषा: | Inglês |
प्रकाशित: |
Public Library of Science
2011
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विषय: | |
ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3102745/ https://ncbi.nlm.nih.gov/pubmed/21637788 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002077 |
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