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MecA dampens transitions to spore, biofilm exopolysaccharide and competence expression by two different mechanisms

The adapter protein MecA targets the transcription factor ComK for degradation by the ClpC/ClpP proteolytic complex, thereby negatively regulating competence in Bacillus subtilis. Here we show that MecA also decreases the frequency of transitions to the sporulation pathway as well as the expression...

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Bibliographische Detailangaben
Hauptverfasser: Prepiak, Peter, Defrancesco, Melissa, Spadavecchia, Sophia, Mirouze, Nicolas, Albano, Mark, Persuh, Marjan, Fujita, Masaya, Dubnau, D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3102577/
https://ncbi.nlm.nih.gov/pubmed/21435029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2958.2011.07627.x
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