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Herpesviral replication compartments move and coalesce at nuclear speckles to enhance export of viral late mRNA

The role of the intranuclear movement of chromatin in gene expression is not well-understood. Herpes simplex virus forms replication compartments (RCs) in infected cell nuclei as sites of viral DNA replication and late gene transcription. These structures develop from small compartments that grow in...

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Hlavní autoři: Chang, Lynne, Godinez, William J., Kim, Il-Han, Tektonidis, Marco, de Lanerolle, Primal, Eils, Roland, Rohr, Karl, Knipe, David M.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3102408/
https://ncbi.nlm.nih.gov/pubmed/21555562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1103411108
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