Endocytosis of EphA receptors is essential for the proper development of the retinocollicular topographic map

Endocytosis of Eph–ephrin complexes may be an important mechanism for converting cell–cell adhesion to a repulsive interaction. Here, we show that an endocytosis-defective EphA8 mutant forms a complex with EphAs and blocks their endocytosis in cultured cells. Further, we used bacterial artificial ch...

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Main Authors: Yoo, Sooyeon, Kim, Yujin, Noh, Hyuna, Lee, Haeryung, Park, Eunjeong, Park, Soochul
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2011
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3102278/
https://ncbi.nlm.nih.gov/pubmed/21343910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.44
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