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The Escherichia coli RNA polymerase α subunit linker: length requirements for transcription activation at CRP-dependent promoters

The C–terminal domain of the Escherichia coli RNA polymerase α subunit (αCTD) plays a key role in transcription initiation at many activator-dependent promoters. This domain is connected to the N–terminal domain by an unstructured linker, which is proposed to confer a high degree of mobility on αCTD...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Veröffentlicht in:EMBO J
Hauptverfasser: Meng, Wenmao, Savery, Nigel J., Busby, Stephen J.W., Thomas, Mark S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2000
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC310225/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10747024/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/19.7.1555
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