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BACOM: in silico detection of genomic deletion types and correction of normal cell contamination in copy number data
Motivation: Identification of somatic DNA copy number alterations (CNAs) and significant consensus events (SCEs) in cancer genomes is a main task in discovering potential cancer-driving genes such as oncogenes and tumor suppressors. The recent development of SNP array technology has facilitated stud...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3102226/ https://ncbi.nlm.nih.gov/pubmed/21498400 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btr183 |
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