BACOM: in silico detection of genomic deletion types and correction of normal cell contamination in copy number data

Motivation: Identification of somatic DNA copy number alterations (CNAs) and significant consensus events (SCEs) in cancer genomes is a main task in discovering potential cancer-driving genes such as oncogenes and tumor suppressors. The recent development of SNP array technology has facilitated stud...

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Bibliographic Details
Main Authors: Yu, Guoqiang, Zhang, Bai, Bova, G. Steven, Xu, Jianfeng, Shih, Ie−Ming, Wang, Yue
Format: Artigo
Language:Inglês
Published: Oxford University Press 2011
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Original Papers
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3102226/
https://ncbi.nlm.nih.gov/pubmed/21498400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btr183
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