Murine Prkdc Polymorphisms Impact DNA-PKcs Function

Polymorphic variants of DNA repair genes can increase the carcinogenic potential of exposure to ionizing radiation. Two single nucleotide polymorphisms (SNPs) in Prkdc, the gene encoding the DNA-dependent protein kinase catalytic subunit (DNA-PKcs), have been identified in BALB/c mice and linked to...

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Bibliografski detalji
Glavni autori: Fabre, Kristin M., Ramaiah, Lila, Dregalla, Ryan C., Desaintes, Christian, Weil, Michael M., Bailey, Susan M., Ullrich, Robert L.
Format: Artigo
Jezik:Inglês
Izdano: 2011
Teme:
Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3102216/
https://ncbi.nlm.nih.gov/pubmed/21265624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1667/RR2431.1
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