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Triostin A derived hybrid for simultaneous DNA binding and metal coordination
The natural product triostin A is known as an antibiotic based on specific DNA recognition. Structurally, a bicyclic depsipeptide backbone provides a well-defined scaffold preorganizing the recognition motifs for bisintercalation. Replacing the intercalating quinoxaline moieties of triostin A by nuc...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Springer Vienna
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3102191/ https://ncbi.nlm.nih.gov/pubmed/20967559 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00726-010-0764-3 |
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