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Synthesis and preliminary evaluation of radiolabeled bis(zinc(II)-dipicolylamine) coordination complexes as cell death imaging agents

The aim of this study was the development of (99m)Tc labeled bis(zinc(II)-dipicolylamine) (Zn(2+)-DPA) coordination complexes, and the in vivo evaluation of their usefulness as radiotracers for the detection of cell death. DPA ligand 1 was labeled with (99m)Tc via the (99m)Tc-tricarbonyl core ([(99m...

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Detalhes bibliográficos
Main Authors: wyffels, Leonie, Gray, Brian D., Barber, Christy, Woolfenden, James M., Pak, Koon Y., Liu, Zhonglin
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3102142/
https://ncbi.nlm.nih.gov/pubmed/21570306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2011.04.029
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