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Structure of the C-terminal laminin G-like domain pair of the laminin α2 chain harbouring binding sites for α-dystroglycan and heparin
The laminins are large heterotrimeric glycoproteins with fundamental roles in basement membrane architecture and function. The C–terminus of the laminin α chain contains a tandem of five laminin G–like (LG) domains. We report the 2.0 Å crystal structure of the laminin α2 LG4–LG5 domain pair, which h...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Oxford University Press
2000
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC310212/ https://ncbi.nlm.nih.gov/pubmed/10747011 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.7.1432 |
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